Session (CTI)

Issue: Building on the conversation from ISPOR Montreal 2025, this panel will feature European, UK and US perspectives to take a deep dive into how to undertake a societal perspective cost-effectiveness analysis. The panel will discuss a set of case studies across different disease areas that have cost-effectiveness analysis results that have shown to move in both expected and unexpected directions. Methods for capturing societal perspective inputs will be compared and results illustrated. The issue panel will go beyond what should or should not be included in a societal perspective analysis, to thinking about how it is included and what the implications could be – sometimes unintended. The opportunities and challenges of alternative methods will be discussed. The use of a consistent cost-effectiveness threshold regardless of which outcomes are included will be debated and the additional consequences of taking a societal perspective will be highlighted. For example, what might a societal perspective analysis mean for cross-sector collaboration and are we prepared? Overview: Dan Ollendorf (10 minutes) will introduce the discussion by outlining what a societal perspective cost-effectiveness analysis is intended to inform, the case studies that will be covered, and the societal domains that will be highlighted. Saskia Knies (10 minutes) will share ZIN’s approach to societal perspective analysis and share examples of how societal domains were captured in the focused case studies. Simone Sutherland (10 minutes) will highlight considerations from the same case studies and share a technology developers’ perspective on the importance of the societal perspective. Praveen Thokala (10 minutes) will reflect on the case studies presented and emphasize the implications of broader perspective on the opportunity costs considered. The audience will be engaged with interactive polling and Q&A to collectively prioritize how societal perspective domains should be captured in analyses and discuss priorities for future work.