Raising the Bar on RWE for Publication: A Discussion with Leading Journal Editors
Moderator
Sebastian Schneeweiss, ScD, MD, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States
Speakers
Shirley Wang, PhD, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States; Christine Laine, MD, MPH, Annals of Internal Medicine, Philadelphia, PA, United States; Gregory Curfman, MD, Journal of the American Medical Association (JAMA), Boston, MA, United States; Daniel Solomon, MPH, MD, Arthritis and Rheumatology, Boston, MA, United States
Real-world evidence (RWE) is increasingly used to inform regulatory, HTA, and payer decisions, as well as clinical guidelines. Yet, acceptance of RWE in leading journals—particularly clinical journals-- remains inconsistent. Concerns relate to causal methods and findings, transparency, bias, and reproducibility. This session will identify some of the most pressing challenges in reviewing and accepting RWE studies and what leading editors look for to meet high quality expectations for RWE, before transitioning to identify tools, training and practices that can support its publication. The objective of this session is two-fold: (1) identifying the problems when working to publish high quality RWE to a journal, and (2) proposing and reacting to solutions to the presented problems with an overview of best practices and existing tools to support its acceptability. The session will engage audience members by inviting them to react to proposed solutions along with the journal editors for the final 10 minutes, along with the Q&A.
Topic
Organizational Practices, Real World Data & Information Systems, Study Approaches