Author(s)
Rafael Gálvez, MD, Pain Clinic and Palliative Care1, Antonio Pardo, MD, Psychologist2, Jose Miguel Cerón, MD, ------3, Fernando Villasante, MD, ------4, Jose Luis Aranguren, MD, ------5, María Teresa Saldaña, MD, --6, Ana Navarro, MD, ------7, Miguel Angel Ruiz, PhD, Lecturer2, Silvia Díaz, PD, ------8, Javier Rejas, MD, Outcomes Research Manager91University Hospital “Virgen de las Nieves”, Granada, Spain; 2 Universidad Autónoma de Madrid, Madrid, Spain; 3 Primary Care Centre “San Antonio”, Motril, Granada, Spain; 4 Primary Care Centre “José Marvá”, Madrid, Spain; 5 Clínica MADRID, Fuenlabrada, Madrid, Spain; 6 Primary Care Centre “Raíces”, Castrillón, Asturias, Spain; 7 Primary Care Centre “Puerta del Ángel”, Madrid, Spain; 8 Euroclin Institute, Madrid, Spain; 9 Pfizer Spain, Madrid, Spain
OBJECTIVES: To achieve a linguistic adaptation and psychometric validation into Spanish of the ID Pain questionnaire for the screening of differential diagnosis of pain with a neuropathic component. METHODS: Cross-sectional validation study carried out in two phases: cultural adaptation into Spanish language and validation study to test psychometric properties of the scale in men and women >18 years, with neuropathic (NP) and noniceptive (NNP) chronic pain for more than 6 months. Scale properties of feasibility, reliability and validity were evaluated according to clinical and LANNS scale reference diagnosis. Factor and ROC curves analysis, agreement with reference diagnosis and determination of sensitivity and specificity values were assessed. RESULTS: A total of 283 subjects (64.4% women; mean age: 59.1+14.9 years), 145 (51.2%) with NP and 138 (48.8%) with NNP were included in the study. Time to completion of questionnaire was 4.2 (3.0) minutes, and 15% of patients needed some help to complete it only. Factor analysis showed a one-dimension scale only, explaining the 37.5% of total variance. The instrument was time-stable (test-retest r-Pearson= 0.98, p<0.0005). Mean score differentiated NP from NNP patients; 3.5 (1.2) vs. 1.2 (1.4); p<0.0005. Optimum cut-off value was >3 points, showing an AUC = 0.89; p<0.0005, sensitivity value of 0.807, specificity of 0.841 and kappa coefficient of agreement with reference clinical diagnosis of 0.65. The scale also showed good concurrent validity with LANSS classification of subjects; kappa 0.61; p<0.0005. CONCLUSION: The Spanish version of the ID Pain questionnaire is feasible, reliable and appropriated as a self-administered screening tool for pain with a neuropathic component.
Conference/Value in Health Info
2007-10, ISPOR Europe 2007, Dublin, Ireland
Value in Health, Vol. 10, No. 6 (November/December 2007)
Code
PPN10
Topic
Patient-Centered Research
Topic Subcategory
Patient-reported Outcomes & Quality of Life Outcomes
Disease
Systemic Disorders/Conditions
