OBJECTIVE: The purpose of this study was to determine the impact on quality of life, level of compliance and satisfaction with services after pharmacist outpatient counseling and monitoring. METHOD: The study is a prospective examination of hypertensive patients over 64 years old. The control group (N =160) received standard drug counseling on receiving new medication. The treatment group (N = 144) received extensive drug education and monthly follow-up calls for reassessment and to reinforcing compliance. The patients filled out health status surveys at the start of the study (T0), in 6 months (T1) and 12 months later (T2). The survey instruments included Pharmacy Services satisfaction, the Morisky Compliance Scale, medication awareness, smoking, liquor, Likert Scale self assessment of global health (0 –100 in 10 unit decrements) , SF-36, HUI Mark 2, and the Hypertension/Lipid TyPE Survey. RESULTS: The groups were compared to each other at T0 and T2, and compared to themselves from T0 to T2. The difference between groups in Morisky Score and Likert Scale was not significant and neither group had significant changes. At T2 the treatment group had a higher SF-36 RE score than the control group, 79.06 vs. 67.42 (p<0.05) while other scales showed no significant differences between groups or changes over time. The difference between groups in HUI attributes or utility score was not significant and neither group had significant changes. CONCLUSION: Patient counseling does not appear to enhance compliance in this population. QoL scores indicate some emotional benefit, possibly due to ongoing pharmacist contact. Other measures in this population suggest no impact on overall level of health based on outpatient counseling.