Psoriasis is a chronic disease, which affects 4.7 % of the French population. Even if it is not a question of a vital prognosis, it is a very invalidating condition in daily life because of the damage to the body image. OBJECTIVE: Evaluate the Quality of Life consequences for patients with psoriasis, in France. METHOD: Four thousand five hundred anonymous questionnaires were sent, via a Patient Support Group acting against Psoriasis (Association Pour la Lutte Contre le Psoriasis, APLCP). The questionnaires consisted of two scales: the Psoriasis Disability Index and 10 questions concerning the treatment and evolution of psoriasis. RESULTS: Twenty-five days after the mailing, 2014 questionnaires (44%) were received. An analysis of the first questionnaire was conducted. The respondents were 54% women and their average age was 50 years, whereas for men, 53 years. The average age at diagnosis for men was at 30 years, for women, at 25 years. Women are significantly more adversely affected than men in their everyday activities. Men are significantly more adversely affected than women at work. No difference was observed between men and women for the global score. Psoriasis seems to incapacitate 16-55 year olds in their social relations, leisure activities and how well they keep their house more than it does older subjects. Long-standing psoriasis does not seem to be more of a handicap to people than more recent psoriasis. The global score is similar. However, a clear trend is observed between the age at the moment of diagnosis and the level of incapacity (p = .0176). The younger the individual in which psoriasis is diagnosed, the higher the level of incapacity. This is particularly marked in terms of the everyday and leisure scores. CONCLUSION: These results highlight the value of appropriate and relevant psychological and medical environment for children suffering from psoriasis.