COST-EFFECTIVENESS OF DEMENTIA CARE MANAGEMENT ALONGSIDE A CLUSTER-RANDOMIZED CONTROLLED INTERVENTIONAL DELPHI TRIAL

Author(s)

Michalowsky B1, Xie F2, Kaczynski A3, Hoffmann W1
1German Center for Neurodegenerative Diseases, Greifswald, Germany, 2McMaster University, Hamilton, ON, Canada, 3German Center for Neurodegenerative Diseases (DZNE), Greifswald, Germany

OBJECTIVES: To determine the incremental cost-effectiveness ratio (ICER) of a collaborative dementia care management versus usual care in Germany.

METHODS: The cost-utility analysis was based on the data collected from 444 patients and conducted alongside the general-practitioner based, cluster-randomized, controlled interventional trial DelpHi-MV (Dementia: Life- and Person Centred Help in Mecklenburg-Western Pomerania Germany) that was initiated to evaluate a collaborative dementia care management aiming to provide optimal treatment and care. The healthcare resource uses and corresponding unit costs were used to calculate the costs from a public payer’s perspective. Preference-based health utility values assessed using the SF-6D were used to estimate quality-adjusted life years (QALYs). The ICER was calculated using the incremental cost per QALY gained by the dementia care management program compared with usual care at 24 months using a wide range of willingness-to-pay (WTP) margins.

RESULTS: At the base-case analyses, compared with usual care, the dementia care management was associated with higher QALY (1.35 vs. 1.30) and lower cost (24,046€ vs. 24,615€) after 24 months. The probability of the management approach being cost effectiveness was 88% and 95% at willingness to pay thresholds of 40,000€ and 80,000€ per QALY gained, respectively. Scenario analyses with complete cases, protocol-driven costs removed, and truncated extremely high-cost patients confirmed the robustness of the cost effectiveness at baseline.

CONCLUSIONS: The dementia care management increased QALYs and reduced costs compared with the usual care. Therefore, an implementation into routine care could be beneficial for both patients and health care payers.

Conference/Value in Health Info

2018-11, ISPOR Europe 2018, Barcelona, Spain

Value in Health, Vol. 21, S3 (October 2018)

Code

CE3

Topic

Economic Evaluation

Topic Subcategory

Cost-comparison, Effectiveness, Utility, Benefit Analysis

Disease

Neurological Disorders

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