OBJECTIVES: Analize the correlation among different questionnaires of quality of life and FEV1 in patients with COPD. METHODS: Cross-sectional study of 126 patients with COPD controlled in a primary care setting. Non-random sample. Patients were asked to fill in five questionnaires of quality of life (Euroquol, Coop-Wonca vignettes –CW-, Nottingham Health Profile –NHP-, Saint George Respiratory Questionnaire –SGRQ- and de Basal Dyspnoea Index –BDI-) and they also performed a forced spirometry. Other variables measured were: age, sex, study level, marital status, comorbidity, and prescribed treatment. RESULTS: A total of 88.9% males, age (mean+ std) 68.5+8.5 years, 32% illiterates, 87% married; 70% received bronchodilator treatment; 74% had at least another comorbid condition; FEV 1 57.2% + 19.5%. Quality of life was moderately affected: Euroquol visual scale (6.2+2.1), C-W physical activity (3.6+0.9), C-W feelings (2.1+1.1), C-W daily activities (2.2+0.1), C-W social activities (1.8+1.3), C-W change in health status (2.5+0.8), C-W health status (3.5+0.9), C-W pain (2.5+1.3), C-W social support (2.0+1.0), C-W quality of life (2.4+0.7), NHP total (31.5.2+22.8), SGRQ (36.4+21.6), BDI- functional impairment (2.9+0.9), BDI-magnitude of work (2.9+0.9), BDI-magnitude of effort (2.9+0.9). spearman Correlation coefficient was statistically significative among all the QOL questionnaires excepted between Euroqol and BDI-magnitude of work. This correlation was mild-moderate (r <0.5). FEV1 correlated with BDI, SGRQ, C-W physical activity, C-W daily activities, C-W health status (r=0.41; r=0.38, r= -0.19, r= -0.27, r= -0-21, respectively). Correlation was moderate-high among BDI, NHP, SGRQ, and COOP-Wonca Vignetes (r>0.5). CONCLUSION: Quality of life in patients with COPD is slightly correlated with functional status (specially specific respiratory questionnaires and several vignettes of COOP-WONCA questionnaire). There is a good correlation between generic and specific QOL questionnaires in patients with COPD.