Very common in infants, gastroesophageal reflux causes regurgitations which generally disappear during the first year of life (or before the infant starts walking). Diagnosis was made in 18% of cases during a statistical study carried out among infants which were theoretically in good health. Although rarely or not at all evaluated, the impact of GER in infants upon the everyday life of the parents is undoubtedly far from negligible. OBJECTIVES: To evaluate the impact of GER in infants upon the quality of life of both parents. METHOD: Within the context of a cohort, 150 infants (under 3 months of age) were monitored over a period of 6 months. On inclusion, a generic scale (SF-12) are completed by both parents. The completed questionnaires were returned in prepaid envelopes. RESULTS: The first results concerned the first 40 patients. Regarding the SF-12, the results were organised in 2 scores: mental (MCS-12) and physical (PCS-12). The norms observed in a standard American population are a score of 50 (e-t:10) for each dimension. The SF-12 scores for the fathers on inclusion were: PCS-12=52.6 (4.5) & MCS-12=44.7 (8.4). The SF-12 scores for the mothers on inclusion were: PCS-12=47.4 (7.7) & MCS-12=36.0 (9.8). Paired comparison of these results shows a modification in the quality of life of the mother compared with that of the father. This difference is significant in both dimensions (p<0.005). CONCLUSION: The quality of life, evaluated by the SF12, of the parents whose child suffered from gastroesophageal reflux was modified; this phenomenon was particularly marked with regard to the ''mental'' component. The quality of life of the mother was, in our study, more modified than that of the father. The impact upon the quality of life of the immediate entourage was, once again, highlighted. This impact should be taken into consideration in the treatment of the infant.