THE EFFECT OF TRADITIONAL MEDICINE ON QUALITY OF LIFE IN PATIENTS WITH ATOPIC DERMATITIS- A REVIEW OF RECENT CLINICAL TRIALS
Author(s)
Ko Y, Cheon C, Jang B, Ko S
Kyung Hee University, Seoul, South Korea
OBJECTIVES: This study aims to review the impact of traditional medicine treatment on the quality of life(QoL) of the atopic dermatitis(AD) patients. METHODS: We searched the PubMed, Oasis, NDSL, RISS, CNKI and J-Stage for published papers. We included randomized controlled trials on traditional medicine for AD which evaluated the improvement of QoL as outcome measurement and excluded animal studies and review papers. We qualitatively analyzed characteristics of the studies by several categories such as origin of trials, diagnostic method, treatment method, QoL assessment method, evaluation of the impact of treatment on patient’s QoL and the incidence of adverse event. RESULTS: We reviewed 98 studies, and finally included 2 published papers in this study. Identified studies were both conducted in China region. All the studies recruited the age range of pediatric patients based on the criteria of Hanifin and Rajka that defined as moderate to severe AD. The types of treatment methods were varied. One was multi-arm trial which divided into a single oral administration of Chinese herbal formula(PTQXT) group, combination of PTQXT with Chinese herbal external wash formula group and positive control group. The other was single use of Chinese herbal medicine concoction compared with placebo drug. The studies measured QoL as general outcome by using certified Chinese version of the Children’s Dermatology Life Quality Index. The result showed that patients’ quality of daily life improved almost 30%(p=0.023, p=0.008). There were no reported adverse events. CONCLUSIONS: The present study showed that we need to conduct more systematic and analytic researches for supporting clinical evidence of QoL improvement of traditional medicine for AD. We hope these valuable evidences can lead to modernize the health policy on traditional medicine for saving patients’ economic burden of disease as well as maintaining the patients’ QoL in the future.
Conference/Value in Health Info
2016-09, ISPOR Asia Pacific 2016, Singapore
Value in Health, Vol. 19, No. 7 (November 2016)
Code
PSS9
Topic
Patient-Centered Research
Topic Subcategory
Patient-reported Outcomes & Quality of Life Outcomes
Disease
Sensory System Disorders