OBJECTIVES: The main aim is to Study the appropriateness and quantify the utilization of antibiotics. METHODS: A Cross Sectional study was conducted in a secondary care referral hospital for a period of three months using the prescriptions of the patients suffering with the various infections RESULTS: Altogether 150 patients, (67.15%) males and 236 (32.85%) females were enrolled. Among these, highest rate of drug prescription was observed for patients aged between 40 to 60 years, which consist of 85(56.6%) patients . Highest rate of antimicrobial prescription was observed for patients of respiratory and urinary tract infections .Highest frequency of drug prescription was observed for Azithromycin which consist of  30.35% which was followed by Amoxicillin 18.12%, Cifixime  (6.52%), Doxycycline  (24.13%),ceftriaxone(12.3%) , ciprofloxacin (8.58%), Overall 76.84% of the patients were treated with a combination therapy of antibiotics, But if antibiotics are not used  rationally then there will be increase chances of resistance of bacteria as also as increase the total cost of treatment and adverse reactions.  CONCLUSIONS: Drug utilization studies are used as powerful tools to ascertain the role of drugs in the management of various diseases. There is a  need of patient education and counseling on use of antimicrobial drugs (AMDs) by the clinical pharmacist.