OBJECTIVES: To explore the knowledge, attitude and use of CAM among pharmacy and medical students at local university in Malaysia. METHODS: A self completed questionnaire was used to obtain data on personal use of CAM, reasons to use, perceived barriers, information sources, knowledge as well as CAM inclusion in curriculum. The survey was taken of 368 pharmacy and medical students enrolled in final year.  RESULTS: A total of 314 responded to the survey giving a response rate of 85%. The mean age was 23(SD±0.692). The sample was comprised of 47(14.9%) males and 267(85.0%) females. CAM use was common among pharmacy 93(56.7%) and less 45(30%) common among medical students with a common belief that CAM are natural and safe to use. Traditional Malay medicines (TMM) was most common CAM followed by Traditional Chinese Medicines (TCM). Students reported to spend an average of RM50-100 per month of CAM.  The most common source of information on CAM was online vendors however lack of scientific evidence was given as barrier to CAM use. Both pharmacy and medical students agreed including CAM in the curriculum however they reported that curriculum is too packed. CONCLUSIONS: Overall students had a favourable attitude including CAM education into the curriculum. Pharmacy students showed more favourable attitude towards CAM compare to medical students. A receptive attitude towards CAM suggested needs for both curriculum development on CAM and extensive research to have evidence on CAM.