OBJECTIVES:: Atopic dermatitis (AD) is a disease with a high burden and impact on quality of life. To date only a few studies have been conducted evaluating the burden of AD in adults. We are conducting a transversal prospective study aiming to evaluate the global burden of AD. METHODS:: This is a cross-sectionnal study that is conducted since December 2016 and will last May 2017. We administrated a questionnaire to evaluate the impact of AD on daily life and included validated tools for the evaluation of disease burden (ABS-A), dermatology specific quality of life instrument (DLQI) and economic impact of AD. In addition, the severity of AD has also been evaluated by using a modified version of the PO-SCORAD. The questionnaires were mailed to adult patients belonging to the French support group for AD. In addition consecutive patients aged more than 18 and attending 4 French dermatology departments were asked to fill in these questionnaires after having obtained their oral consent. RESULTS:: We herein present the intermediate results of this study. Patients having answered were included in the present analysis. A total of 225 patients answered the questionnaires including 149 women and 76 men. Of the 225 patients, 108 declared moderate AD whereas 117 declared severe AD. One out of 4 patients had a disease that began during childhood whereas the aothers had an adult onset AD. In total, 71% of patients were followed-up by their dermatologist for their disease with significantly more patients with severe AD. Mean DLQI and ABS-A were respectively 19,6 (SD 5.7) and 47.6 (SD 15.2) in patients declaring severe AD and 13.7(SD 5.8) and 31.9(SD 14.1) in those declaring moderate AD. (p<0,001). CONCLUSIONS:: Our intermediate results showed that the burden of AD increase with the severity of AD and that AD impacts not only daily life but also professional activity and sexuality.