OBJECTIVES::  This study aims to describe the clinical advantages of using ultrasonic technology versus conventional electrosurgery in GYN oncology procedures to reduce perioperative and postoperative complications in surgical staging, including lymphadenectomy. METHODS::  An Ovid Embase/Medline, Scopus and PubMed search were conducted using keywords such as harmonic, ultrasonic, ultracision, scalpel, shears, scissor and dissector in procedures including but not limited to gynecologic surgery, genital diseases/neoplasms (female), hysterectomy, myomectomy, adenoma, cervix, carcinoma, neoplasm, tumor and malignancy. Results were limited to publications of human subject studies in English from January 2006 to October 2016. Studies comparing ultrasonic technology to conventional electosurgery for GYN oncology were selected. All abstracts were filtered, including meta-analysis, RCTs, retrospective observational studies. Case studies and review articles were excluded. RESULTS::  Four studies (one prospective and three retrospective cohort reviews) were identified from France, Italy, Czech Republic and Qatar for para-aortic lymphadenectomy or surgical staging as part of concomitant laparoscopic procedures (hysterectomy, pelvic lymphadenectomy, omentectomy, ovary transposition) and radical vulvectomy with inguinal lymphadenectomy. All studies describing ultrasonic technology demonstrate significant benefits over conventional techniques in gynecologic oncology surgery: Intra-operative peritoneal leakages are reduced by 76% (from 14% to 3%, p=0.004), blood loss during surgery is reduced up to 54% (from 75.4 cm to 34.7 cm, p=0.01), operative time for tissue excision is up to 18% less (from 142 min to 117 min, p<0.05), at most 32% additional lymph nodes are harvested (from 13.7 to 18.1, p<0.001) and up to a 100% reduction in lymphocele leaks post-operative that require treatment (from 7 to 0, p=0.03). CONCLUSIONS:: Although a limited number of clinical studies evaluating ultrasonic technology for GYN oncology exist, current studies show that ultrasonic technology demonstrates significant patient benefits compared to conventional electrosurgery techniques. Benefits, however, need to be confirmed in prospective randomized trials.