UNDERSTANDING THE JAPANESE GENERAL PUBLIC'S RATIONALE FOR TRADES IN A TIME-TRADE-OFF ASSESSMENT FOR SYSTEMIC LUPUS ERYTHEMATOSUS
Author(s)
Crawford B1, Kim HR2, Wada K3
1Japan & APAC, IMS Health KK, Tokyo, Japan, 2The University of Tokyo, Tokyo, Japan, 3Adelphi Values, Tokyo, Japan
OBJECTIVES: There is a growing need to evaluate utilities for disorders within the Asian region to be used in cost-effectiveness analyses. However, there has been some concern about the legitimacy of direct utility elicitation among Asian subjects. To understand the thinking of subjects responding to a time-trade-off assessment, subjects were asked to describe what they considered when making their trade. Understanding their rationale will provide insights into the values of respondents. METHODS: Utility and demographic data were collected from 101 subjects from the general public in Tokyo. Subjects responded to six hypothetical systemic lupus erythematosus health states, described by six levels of severity, and provided their valuation of their utility through a visual analog scale and time-trade-off. One health state was randomly selected (excluding the anchor state) for each respondent to provide their rationale for their trade. RESULTS: Respondents were comprised of 54 men and 47 women. Subjects provided a range of responses from concerns of family burden to self-preservation (“Prefer to live as long as possible”) and needing to finish personal commitments and “Dignity / Pride” by not wanted to ask others for any assistance. “Unable to bear symptoms / Prefer to die” was the most frequently provided response (~30%) followed by “Burden on family / others” (~20%). Subjects who responded to the mild health state had a tendency to respond “Able to tolerate symptoms” over other reasons when assessing their trade. Younger subjects were more likely to respond with “Hope for a cure”. CONCLUSIONS: Our study found that subjects were able to provide valid utility estimates from the time-trade-off. The rationale for trade-offs provide insights into how responses are formulated within an Asian country. Additional research will need to be conducted to compare these results to other Asian and Western countries.
Conference/Value in Health Info
2014-09, ISPOR Asia Pacific 2014, Beijing, China
Value in Health, Vol. 17, No. 7 (November 2014)
Code
PSY7
Topic
Patient-Centered Research
Topic Subcategory
Health State Utilities
Disease
Systemic Disorders/Conditions