OBJECTIVES: Report of health-related quality of life (HRQOL) among cervical cancer patients in Indonesia is very rare. This study aimed to examine the HRQOL of cervical cancer patients in Indonesia using EQ-5D-3L. METHODS: A cross-sectional survey was conducted in 87 cervical cancer patients admitted to Dr. Sardjito Hospital, a referral hospital in Yogyakarta Province-Indonesia, between June to December 2013. Data on HRQOL was collected using EQ-5D-3L (Indonesian version). As no Indonesian-EQ-5D-3L value set exists, Malaysian value set was used to calculate utility among these patients. RESULTS: About 14%, 51%, 31% and 5% of patients were in stage I to IV, respectively. The most frequently reported problems were pain/discomfort (67.82%) and anxiety/depression (57.47%). The mean of EQ-5D VAS score was 75.83 (SD=17.03). The mean utility value was 0.830 (SD=0.182), 0.751 (SD=0.188), 0.704 (SD=0.205), and 0.766 (SD=0.131) for patients with stage I to IV, respectively. Based on the stage of cervical cancer, the proportion of patients reporting problems in each dimension tended to increase from stage I to stage IV while the EQ-5D VAS score tended to decrease from stage I to stage IV. The utility value also tended to decrease from stage I to stage III, however it rather increased for patients with stage IV. CONCLUSIONS: Cervical cancer significantly affects patient’s HRQOL. Effort should be made to improve the quality of life of cervical cancer patients especially in term of pain /discomfort and anxiety/depression reduction.