The Archimedes Model is a carefully validated, clinically realistic, simulation model of diseases and healthcare. By using advanced methods of mathematics, computing, and data systems, the Model enables researchers and decision makers to make better informed decisions. The Archimedes Model includes a wide range of diseases/conditions (diabetes, cardiovascular diseases, COPD, obesity, cancers) and detailed descriptions of healthcare delivery systems, interventions, tests, and treatments and patient and physician behaviors. The Model has been used by many organizations (e.g. goverments, pharmaceutical companies, insurance companies, disease organziations) accross the globe to help answer a wide variety of questions related to clinical trials, policy setting, performance measurement, and health economics and outcomes research. The Model has been adapted to a wide range of settings including US, UK, France, Italy, Sweden, Norway, Poland, Japan, Brazil, and California. We will highlight a number of projects that were supported by EU and Japan, in which the Model was used to guide decision making around management of diabetes. We will also discuss the potential applications of adapting the Archimedes Model to other Asian countries (e.g. India or China)  beyond Japan.