OBJECTIVES: Reforming experience of health care in Western countries (Canada, USA, UK and other European countries) demonstrates the need for standardization of medical and pharmaceutical care for population, taking into account the results of pharmacoeconomic analysis, it can reduce health care costs by 10-20 %.In Ukraine Prof. Olha Zalis’ka conducted theoretical bases and pharmacoeconomic analysis and creation of educational and methodical system of pharmacoeconomics for pharmacists during 1999-2003. METHODS: From 2003 the study of discipline “Pharmacoeconomics” was included in curriculum of pharmacists on specialty "Pharmacy" and "Clinical Pharmacy" and for postgraduate training of pharmacists in the specialty "Economy and management of pharmacy " and "General pharmacy "in Ukraine. RESULTS: Zalis'ka Olha defended doctoral thesis "The theoretical basis and practical use of Pharmacoeconomics in Ukraine " in 2004. It was published 5 manuals “Pharmacoeconomics” (2000), “The Bases of Pharmacoenomics (2002), 2007, 2014, which approved by Ministry of Health and Ministry of Education and Science of Ukraine for using of 20 pharmaceutical faculties of medical universities.In 2008 we created ISPOR Ukraine Chapter at the Danylo Halytsky Lviv National Medical University (www.ispor.org / local_chapter / Ukraine) . USPOR develops and implements the theoretical, practical and educational areas of pharmacoeconomics in Ukraine. To spread knowledge and increase access of local experts set up special website in ukrainian (www.uspor.org.ua), which presents the main domestic results. In the postgraduate training of pharmacists we use distance learning program (IDL), which are available in Ukrainian. CONCLUSIONS: We implemented the pharmacoeconomics in requirements of the "Concept of Pharmaceutical Sector of Health during 2011-2020", which claim the use of pharmacoeconomics methods in governmental programs, providing formulary system for in-patients.We work in  MoH Commission of Ukraine which integrates the results of pharmacoeconomic studies into practice to determine the list of  medicines for state programs for social health insurance.