OBJECTIVES: Disinvestment of existing low- or no-added value technologies can be used as a tool to improve access to effective, adapted and efficient technologies, whilst ensuring the long-term sustainability of healthcare systems. The objective of this SLR was to identify disinvestment practices and proposals in LAC. METHODS: In February 2015, MEDLINE, MEDLINE In-Process, EMBASE, The Cochrane Library and LILACS were searched for relevant articles without date or language limits. The search strategy included terms related to “disinvestment”, “reallocation”, “obsolete technologies” and Latin America. Additionally, a manual search of documents from Latin American Health Technology Assessment agencies was performed. Search results were evaluated by two independent reviewers, with any disagreements resolved through consensus or third-reviewer arbitration. RESULTS: