OBJECTIVES: Decision-makers used economic evaluations to allocate resources, prioritize programs or minimize costs. Panels of experts are one of the methods used by economic evaluators to gather the necessary information to construct models, such as the Delphi technique. Given the limitations of the surveillance of STDs in Ecuador, it is not surprising that no data is available of the disease burden to diagnose and treat diseases caused by HPV. METHODS: The main objective of the study is to reach a consensus of the local clinical practices in the diagnosis and treatment of genital warts caused by HPV and the market-based costs of medical specialists' time, resources, and medical supplies from a societal perspective. RESULTS: The diagnostic method of preference of medical specialists in Ecuador is the vulvar colposcopy followed by the biopsy with a histopathology study. Medical specialists prefer to use pharmacological treatments to resolve the presence of genital warts using Trichloroacetic acid (TCA). Surgical treatment was not favored by panelists. The cost per patient to diagnose and treat is between $395 and $484 USD per patient. The biggest variation is dependent on the price of medical consultations and the frequency of visits depending of the treatment path offered. CONCLUSIONS: The prevention of genital warts caused by HPV has the fundamental purpose to alleviate the morbidity of days lost from disability and the societal economic burden of its treatment. Preventive vaccination can prevent the morbidity burden of genital warts plus the potential of precancers and cancers.