OBJECTIVES: Created in 2002, the Patient-Reported Outcome and Quality of Life Instruments database (PROQOLID) provides a detailed description of 713 generic or disease-specific assessment tools on the Internet (www.proqolid.org). The objective of this study is to identify the PRO instruments available for use in Taiwan. METHODS: The PROQOLID database was explored using the search engine and selecting in the field language the key words “Chinese for Taiwan.” RESULTS: Forty-four questionnaires were identified representing 6.17% of the instruments available in PROQOLID. Out of these 44 questionnaires, six were generic (e.g., Duke Health Profile, Euroqol EQ-5D, Psychosocial Impact of Assistive Device Scale, Ferrans and Powers Quality of Life Index, SF-12 Health Survey, and SF-36 Health Survey). Fourteen different therapeutic areas were identified (e.g., endocrine, system diseases, neoplasms, respiratory tract diseases, nervous system diseases, or psychiatric disorders), representing 33 different indications. Only two questionnaires were available for pediatric use (i.e., the Pediatric Quality of Life Inventory Diabetes Module and the Pediatric Quality of Life Inventory Cancer Module). Asthma was the most frequent indication (four questionnaires available), followed by diabetes mellitus (three questionnaires), Benign Prostatic Hyperplasia (BPH) (two questionnaires) erectile dysfunction (two questionnaires) and Pain (two questionnaires). Within the therapeutic area of neoplasms, four different indications were identified (breast, cervix, lung, and ovary). Only one instrument was available for use in Parkinson’s disease (Parkinson’s Disease Questionnaire – PDQ-39), and one for use in Alzheimer’s disease (Clinical Dementia Rating). Not a single instrument was identified in therapeutic areas such as bacterial infections, eye diseases, virus diseases (e.g., AIDS) or otorhinolaryngologic diseases (e.g., rhinitis). CONCLUSIONS: Results of this overview show that PRO instruments available for use in Taiwan cover a wide variety of indications. Some therapeutic areas, however, are either not very well represented (e.g., pediatrics or nervous diseases) or not at all (e.g., infectious diseases).