HEALTH-RELATED QUALITY OF LIFE AFTER PERCUTANEOUS CORONARY INTERVENTION IN PATIENTS WITH ACUTE CORONARY SYNDROMES

OBJECTIVES: : This study sought to investigate the health status outcomes (health-related quality of life and utility weights) after percutaneous coronary intervention (PCI) in patients with acute coronary syndromes (ACS). METHODS: This was a prospective observational study targeted for the patients underwent PCI with ACS in 48 tertiary hospitals. We assessed the ACS-specific health status (with the use of the Seattle Angina Questionnaire [SAQ]) and the general health status (with the use of the EuroQOL Visual Analogue Scale [EQ-VAS] and EuroQOL 5-Dimensional Classification [EQ-5D]) within 1 week after PCI. RESULTS: A total number of  349 patients were included; average 63.4 aged, 67.3% male, 82.2% non-ST-segment elevation ACS (NSTE ACS). The mean (±SD) SAQ scores (which range from 0 to 100, with higher scores indicating better health status) were 78±23 for physical limitations, 41±30 for angina stability, 70±24 for angina frequency, 77±14 for treatment satisfaction, and 48±19 for quality of life. Analyzing by diagnosis class, NSTE ACS patients had the significant lower scores in all SAQ domains than STE ACS. The other health status outomes, mean (±SD) EQ-VAS scores (which range from 0 to 100) were 70±19 and mean (±SD) EQ-5D scores (which mean utility weights, and range from 0 to 1) were 0.80±0.28. In utility weights, NSTE ACS patients (0.78±0.29) also revealed the lower scores than STE ACS (0.87±0.23). The utility weights of female (0.82±0.28) is lower than those of male (0.82±0.28), and older patients  showed lower utility weights (<55 aged: 0.89±0.24, 55~64: 0.81±0.26, 65~74: 0.76±0.31, 0.71±0.29).  CONCLUSIONS: The health status outcomes of disease-specific measure and general measure showed similar tendency. Further follow up survey is needed to explore the health-related quality of life among ACS patients underwent PCI. Comment : The results were described based on the interim results of KOREAN MUSTANG study. The final result will be applied and modified before presentation.