OBJECTIVES: Patient satisfaction is an important patient reported outcome (PRO) that is being used to document the impact of pharmacists’ clinical services, especially in managing patients with chronic conditions. The purpose of this study was to review literature on the validity and reliability of published instruments that have been used to measure patient satisfaction with pharmaceutical care in the community setting. METHODS: A structured search was conducted in five databases (PUBMED, EMBASE, MEDLINE, PsycINFO, and OVID (1998–Feb. 2011) using keywords to identify studies that measured patient satisfaction with pharmaceutical care using survey instruments. Studies conducted outside United States, those which used non-English language questionnaire; abstracts from conferences, reviews, letters or notes were excluded. Studies reporting patient satisfaction results and/or psychometric properties were included. RESULTS: A total of 21 studies were identified that met the selection criteria. The pharmacy practice setting, sample size, study design in evaluating patient satisfaction varied greatly. The survey instruments differed in number of items, response scale and mode of administration. Majority of survey instrument were administered by mail. The response rate varied from relatively low to very high. Patient satisfaction was a secondary outcome in most of these studies. Majority of the studies used self developed, non-validated or modified instrument with items from preexisting instruments. Only few studies reported psychometric properties of the instrument used. Inconsistency in use of instrument measuring patient satisfaction was observed. In general, studies reviewed showed greater degree of overall patient satisfaction with the services. CONCLUSIONS: In majority of studies patient satisfaction was measured using non-validated instruments. There is a lack of comprehensive, valid and reliable instrument for assessing patient satisfaction with pharmaceutical care services in community setting. Use of a standardized survey instrument, sampling and study design will provide valuable insight into patient evaluation of pharmacist services.