COMPARING THE CLINICAL OUTCOMES FOLLOWING URINARY INCONTINENCE TREATMENT

Author(s)

Gábor Vas, JD, PhD student1, Andras Olah, RN, MNS, Senior Lecturer1, Gyorgyi Katona, RN, BNS, Nurse2, Jozsef Betlehem, RN, MNS, PhD, Associate Professor1, Agnes Muller, MSc, Assistant Lecturer1, Jozsef Roznar, MSc, Senior Lecturer3, Ilona Palfi, RN, MSc, PhD, Senior Lecturer1, Peter Cucz, RN, MNS, Assistant Lecturer1, Agnes Varadyne Horvath, RN, MSc, Senior Lecturer1, Andor Sebestyén, MD, MBA, Deputy Director4, Ildikó Kriszbacher, MSc, PhD, Associate Professor1, József Bódis, MD, PhD, DSc, Professor and Dean1, Imre Boncz, MD, MSc, PhD, associate Professor11University of Pecs, Pecs, Hungary; 2 Hospital Baja, Baja, Hungary; 3 University of Pecs, Szombathely, Hungary; 4 National Health Insurance Fund Administration, Pecs, Hungary

OBJECTIVES:Urinary incontinence is a common problem of women’s health in the developed countries. Tension-free Vaginal Tape (TVT) and Trans Obturator Tape (TOT) are the most common minimal-invasive surgical therapy for incontinence treatment. The aim of our study is to compare the clinical outcomes of TVT and TOT surgery. METHODS:We randomly selected 200 women with TVT surgery and 200 women with TOT surgery (n=400) from 3 major Hungarian hospitals. Medical documentation of women underwent TVT or TOT sugary was analyzed retrospectively focusing on the frequency of complications, length of hospital stay, reoperation and vaginal erosion. Statistical analysis was performed by SPSS version 14 and included frequency analysis, confidence interval (CI) and chi square test. RESULTS:We found significantly higher complication rate at women with TVT surgery compared to TOT method: bladder injury (1% TVT versus 0.5% TOT, p=0.0183), abdominal pain (30.5% vs. 16.0%, p<0.0006), dysuria (21.0% vs. 13.0%, p=0.0332), urinary tract infections (13.5% vs. 6.5%, p=0.0196), retention (7.5% vs. 2.0%, p=0.0013), de novo urge (28.5% vs. 16.5%, p=0.007). The average length of hospital stay was also longer in TVT surgery (p<0.001). In case of TOT surgery, we found a significantly higher reoperation rate (2% vs. 6.5%, p=0.0257) and higher rate of vaginal erosion (0.0% vs. 4%, P=0.0043). CONCLUSIONS: Both type of minor surgical intervention can be considered as efficient way of incontinence treatment, however TVT surgery is associated with higher complication rate, longer average hospital stay, therefore TOT method should be the first choice, if applicable.

Conference/Value in Health Info

2008-09, ISPOR Asia Pacific 2008, Seoul, South Korea

Value in Health, Vol. 11, No. 6 (November 2008)

Code

PUK1

Topic

Clinical Outcomes

Topic Subcategory

Comparative Effectiveness or Efficacy

Disease

Urinary/Kidney Disorders

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