THE COURSE OF PREGNANCY AND DELIVERY OUTCOMES IN PATIENTS WITH OVERWEIGHT AFTER IN VITRO FERTILIZATION

OBJECTIVES: To evaluate the character of pregnancy’s course and delivery outcomes in patients with overweight and pregnancy induced by the program (IVF and embryo transfer) and in patients with overweight and self-pregnancy. METHODS: The study involved 126 patients with pregnancy (age 28 to 40 years). The first group included 67 patients with pregnancy induced by IVF and ET, and the second group included 59 patients with self-pregnancy. Statistical processing of the results obtained in the study was produced using the statistical program SPSS 21.0 (SPSS Inc., USA). For estimation of differences of quantitative indexes between groups we used Student's criterion. The differences were considered significant at p<0.05. RESULTS: In the first group 21.3% of patients were overweight while 15.1% of patients belong to class I and II obesity, according to body mass index (BMI). In the second group 9.7% of patients were overweight and 7.6% were obese. The delivery outcomes by caesarean section were observed more frequently in the patients of the first group (to 32%) compared with the second group. Among women with overweight and obese, in the first group glucose intolerance or gestational diabetes was revealed in 12.7% cases, and in the second group these diseases were revealed in 8.2% cases. In both groups, obesity and overweight were associated with age (older than 35 years, p<0.05), hyperglycaemia and hypertension (p <0.001) and macrosomia of the fetus (p>0,05). Macrosomia of the fetus were detected in 82.3% of patients in the first group and in the 42.6% of the cases in the second group. CONCLUSIONS:  The patients with pregnancy induced by the IVF and ET program in comparing with women with self-pregnancy more often had overweight, which was associated with hypertension and hyperglycemia, macrosomia of the fetus.