OBJECTIVES:  To evaluate health-related quality of life (HRQoL) in patients in vintages of end stage renal disease (ESRD). METHODS: The health states related with dialysis intervention was surveyed by face-to-face interview. We assessed HRQoL in terms of the state of health after dialysis. The HRQoL of 301 patients was measured mainly using EQ-5D. HRQoL was assessed using Korean version of the EQ-5D health questionnaire. We defined 3 vintages by treatment: Group 1: from diagnosis to 1year, Group 2: from 1 year to 5 year, Group 3: 5 year over. RESULTS: According to a study that analyzed a target of 154 peritoneal dialysis (PD) and 147 hemodialysis (HD) for the survey, the utility values are as follows. First, HRQoL showed that the mean value reduced greatly in patients who PD than HD. PD value is 0.86, HD value is 0.80. Second, the mean values were arranged in order from Group 1 to Group 3; PD Group 1 0.88, Group 2 0.87, Group 3 0.82; HD Group 1 0.82, Group 2 0.79, Group 3 0.80. CONCLUSIONS: The results shown that HRQoL has improved with peritoneal dialysis as compared to hemodialysis treatment. The treatment vintage has a negative impact on HRQol. HRQoL in end stage renal disease patients is an important outcome measure. Culture and disease specific QOL instruments that assess patients’ objective and subjective experiences covering most aspects of QOL are urgently needed.