OBJECTIVES:  Aggressive behavior from patients and relatives is a serious risk factor for health care workers. Verbal and physical aggression has a negative effect on their work, it can even cause inability to work and career changing in extreme cases. The aim of our study was to assess the frequency of verbal and physical agression towards paramedics and their impact. METHODS:  A quantitative, cross-sectional study was carried out with non-probability convenience sampling. Our sample consists of paramedics working in health care for more than one year (N=100). Demographic data, number of verbal and physical aggression coming from patients or their relatives, assumed cause of agressive behavior and type of help paramedics received was assessed with a self-made questionnaire. SPSS 22.0 was used for calculating descriptive statistics, χ-test and Mann Whitney U test (p<0,05). RESULTS:  Mean age of responders is 38.57±10.73 years. Large part of the sample has experienced some kind of agressive behavior during their career (verbal: >91%, physical: >49%). Number of conflicts containing verbal aggression is more frequent (from patient: 10.50±10.52; from relative: 9.5±11.06), than physical (from patient: 3.21±4.85; from relative: 1.55±0.50). Paramedics who experienced aggressive behavior are more likely to consider career changing, whether it is verbal (from patient: p=0,016; from relative: p=0,045) or physical (from patient: p<0,001; from relative: p<0,001). Main causes of agression according to paramedics are physcotropic drugs (72,73%), toxic condition (63,64%) and psychological disorders (30,30%). None of the responders (0%!) received any kind of conflict management training or training for trauma processing, although 60% of them would like to participate. CONCLUSIONS:  Paramedics are put at a great risk of being confronted by aggressive patients of relatives. It is important to help them at their workplace, training them how to manage conflicts and process trauma.