OBJECTIVES: "De Todo Corazón" (DTC) is a risk management program with the aim of reducing complications and improving the quality of life of patients with cardiovascular risks. The aim of this study was to assess the prevalence of dyslipidemia in patients under program care. METHODS: The study comprised individuals (64.668) of all ages, living in the Colombian Caribbean. Dyslipidemia was defined as the presence of one or more of the following conditions: Triglycerides > 200 mg/dL, or total cholesterol (TC) > 240 mg/dL, or HDL cholesterol < 40 mg/dL, or LDL cholesterol > 100 mg/dl, or currently taking antilipemic agents. RESULTS:  The average age was 64.5 + 13.9 years and 66.5% female. The prevalence of dyslipidemia was 82.5% (IC 82.2-82.8). Prevalence rates of dyslipidemia in men and women were: 32.8% and 67.2%. Prevalence LDL cholesterol > 100 mg/dl and currently taking antilipemic agents was 31.5% (IC 31.1-31.8) and 49.6% (IC 49.2-50.0). CONCLUSIONS: Dyslipidemia was highly prevalent in patients under program care.