OBJECTIVES: This study aimed to assess the level of adherence of hypertensive patients in Quetta, by using MMAS-8 and Hill Bone Compliance Scale. METHODS: A Cross-sectional descriptive study was conducted in Sandeman Provincial Hospital and Bolan Medical Complex to assess the adherence among hypertensive patients of Quetta, Pakistan. Study has been conducted from March to October 2016. Convenience sampling technique was used to collect data. Those patients who were willing to participate and were suffering with hypertension and receiving medication treatment are included in study. MMAS-8 Urdu version and Hill bone compliance scale was used to assess the level of medication adherence. SPSS V 20 used for descriptive and inferential statistics. RESULTS: Respondents mean age was 45.1 years. Majority 223 (55.6%) were. Marital status showed that maximum respondents 361 (90.0%) were married. Majority of respondents 108 (26.9%) were uneducated. Majority 178 (44.4%) were housewives. And Ethnic group showed that maximum respondents 132 (32.9 %) were Pashtun. The MMAS-8 mean score of adherence in hypertensive patients was 3.55. Among 401 majority of patients 306 (76.6%) were poorly adhered to medications. Ninety-four (23.4%) had moderate adherence. While only (0.2%) had good adherence. The mean score of hill bone compliance Scale in hypertensive patients was 24.16, 83.4% (n=336) had imperfect adherence and 16.2% (n=65) have perfect adherence  CONCLUSIONS: It is concluded, patients with hypertension were non-adherence to treatment regimen by using both the questionnaire and both MMAS-8 and Hill Bone Compliance Scale give similar results.