OBJECTIVES: To evaluate the influence of an MI telephonic intervention by pharmacy students on discontinuation of angiotension-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) among Medicare Advantage Plan (MAP) patients with diabetes mellitus (DM) hypertension (HTN). METHODS: A randomized trial was conducted among patients with DM and HTN enrolled in a Texas MAP. Patients who filled an ACEI/ARBs during June, 2014 and had a 6-month proportion of days covered (PDC) <0.80 in the previous 6-months were determined non-adherent (n=5,851) and randomized to intervention or control groups. The intervention was a phone call by pharmacy students on rotation at the MAP followed by 5 monthly follow-up calls. Prior to implementing calls, 11 participating students attended a 3-day MI training. Patients receiving calls were randomly selected from those randomized to intervention until 250 was reached; 500 controls were randomly selected from controls. Refill data during the 6 months following initial call were evaluated to examine discontinuation defined as no record of a ACEIs/ARBs. A multivariate logistic regression model with an outcome of discontinuation vs. not was constructed to control for imbalances in baseline characteristics including age, gender, number of other medication, regimen complexity, low income subsidy (LIS) status, prescriber specialty, comorbidities, 6-month prior hospitalization, baseline 6-month PDC, and Centers for Medicare and Medicaid Services risk score. RESULTS: