A LITERATURE REVIEW OF THE QUALITY OF LIFE BURDEN OF OPIOID-INDUCED CONSTIPATION
Author(s)
Kennedy-Martin T1, Krauter E2, Cai B2, Munro V3, Conway P4
1KMHO Limited, Brighton, UK, 2Shionogi Inc, Florham Park, NJ, USA, 3Synergy Health Economics Limited, London, UK, 4Shionogi Global, London, UK
OBJECTIVES: Opioid-induced constipation (OIC) is a side effect of opioid medication; it has been suggested that it may be more distressing than the pain of the condition itself. The objective of this literature review was to describe studies reporting the quality of life (QoL) burden of OIC. METHODS: A literature review was undertaken to identify studies on the QOL burden of OIC. Six electronic databases (MEDLINE, EMBASE, CDSR, DARE, CENTRAL, HTA) were searched to identify published manuscripts that reported the QoL burden of OIC. In addition, recent abstract books from key pain and health outcome meetings were interrogated to identify relevant research presented at congresses. Results were assessed for relevance by two reviewers and data extracted. RESULTS:
Conference/Value in Health Info
2017-05, ISPOR 2017, Boston, MA, USA
Value in Health, Vol. 20, No. 5 (May 2017)
Code
PGI35
Topic
Patient-Centered Research
Topic Subcategory
Patient-reported Outcomes & Quality of Life Outcomes
Disease
Gastrointestinal Disorders
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