OBJECTIVES: To estimate the social determinants of suicide in young population from poor households in a region of Colombia in 2014. METHODS: Seven municipalities from two Colombian states (Bolívar and Sucre) were studied using a cross sectional survey methodology. A sample of 10.677 young people with public health insurance between 10-24 years old was extracted from a simple random sampling to study sociodemographic characteristics of the young poor population. A multivariate probit model with robust standard errors was conducted to estimate the social determinants of suicide in young population from poor households in Montes de María region of Colombia in 2014. Variables as age, sex, marital status, employment, parent’s education and young perceptions about thoughts of suicide, physical and sexual abuse were included in the model.   RESULTS: Out of the total respondents, 212 (2.05%) young people between 10-24 years reported suicide attempts, wherein 70.8% were females. The mean age of this group is 17.2 years (SD ±3.7). Regarding the multivariate probit model, the pseudo R-square was 0.6537, showing a good association among variables. Young people who have suicide thoughts (β=0.063, p=0.000), who have been victims of physical abuse (β=0.016%, p=0.004), and who have a father with low levels of education (β=0.014, p=0.004), were more likely to commit suicide attempts in contrast with young people that do not have these characteristics. CONCLUSIONS: Results suggest that suicide attempts in young people should be prevented through public health policies which improve levels of education and family dysfunctions, especially in poor young populations.