BACKGROUND: The re-use (re-u) of medical devices (MDs) is increasing its adoption among Latin America (LATAM) due to the attractiveness of generating potential savings in the short term. Most MDs are designed to be single-use (SUD); however, it could be re-used if are reprocessed (a practice that guarantees the device’s integrity, functionality and safety), but this not being available in LATAM. While regionally there are limited regulations and published evidence on re-u, re-sterilization (with physical or chemical agents) is a current practice, without clear understanding on the potential adverse events (AE) and the impact on Patient Safety (PS).  OBJECTIVES: Assess and quantify Central Sterile Supply Department (CSSD) professionals’ perspectives on re-u of MDs in LATAM, while identifying key trends and improvement areas. METHODS: During an educational event held on August 2015th we provided an specific survey to 25 CSSD members to collect feedback about re-u of MDs.  Device type (T) and frequency (N)  , existence of regulations, users perspectives on PS, malfunctioning of the MDs, gender (G), age (A), years of experience (YE) and country of residence (CR) were included. Results are shown as mean and percentage (%). RESULTS: CONCLUSIONS: Despite considerations on AE & PS, re-u is still common in LATAM. Implementation and improvement of PS surveillance mechanisms would be beneficial to avoid AEs in current conditions.