COST-EFFECTIVENESS ANALYSIS OF NEONATAL SCREENING OF CRITICAL CONGENITAL HEART DEFECTS IN CHINA
Author(s)
Gai R
National Center for Child Health and Development, Tokyo, Japan
Presentation Documents
OBJECTIVES: Pulse oximetry as an adjunct to postnatal clinical assessment is a highly accurate tool for the early detection of congenital heart disease (CHD) in newborn infants. As the technique is simple, non-invasive and inexpensive, it has high potential benefits for developing countries. However, certain barriers may impede its wider implementation. In this study, we aim to inform clinical and health policy decisions by assessing the cost-effectiveness of CHD screening in China. METHODS: We developed a cohort model to evaluate the cost-effectiveness of screening all Chinese newborns annually using two possible screening options compared to no intervention: (1) clinical assessment alone, and (2) pulse oximetry as an adjunct to clinical assessment RESULTS: Comparing with no intervention, postnatal clinical assessment is cost-effective with an incremental cost-effectiveness ratio (ICER) of Int$ /DALY, while pulse oximetry as an adjunct to clinical assessment yielded the best health outcomes. Sensitivity analysis showed that when the proportion of timely access to both diagnosis and treatment increased up to 32%, pulse oximetry plus clinical assessment showed the better expected values compared to clinical assessment alone. CONCLUSIONS: In China, screening for CHD is cost-effective and expected to achieve potential health benefits with improvement of accessibility to pediatric cardiological care.
Conference/Value in Health Info
2016-05, ISPOR 2016, Washington DC, USA
Value in Health, Vol. 19, No. 3 (May 2016)
Code
PHS42
Topic
Economic Evaluation
Topic Subcategory
Cost-comparison, Effectiveness, Utility, Benefit Analysis
Disease
Cardiovascular Disorders