OBJECTIVES: Interest in real-life data is high yet its use in decision-making is still limited due to a number of challenges within data collection and analysis to interpretation. Our aim was to gather, capture and analyze real-life data in the context of using patient level data on the example of treatment of the most common gynecological diseases.  METHODS: We used electronic database registry of patients in the Lviv Regional Reproductive Health Centre in 2015. We analyzed 150 e-medical records of women and found out 30 cases diagnosed with endometriosis and adenomyosis. We calculated average costs of medicine treatment course per patient for 3 months duration. We used the weighted average prices from Morion company database (Ukraine) on 01.12.2015 (1 USD = 23,3 UAH). RESULTS: All costs for out-patient care were from the patients’ perspective while all the payments for the prescribed medicines were out-of-pocket. Among the prescribed medicines were hormonal and symptomatic treatment schemes (while in 46% of cases endometriosis was associated with inflammatory gynecological disorders such as salpingitis, cervicitis, bacterial vaginosis) according to the current official clinical protocols for the ambulatory gynecological care in Ukraine (Decree of the MOH No.417 dd 15.07.2011). Hormonal drugs were prescribed in 20% cases: norethisterone (tab. 5 mg) – $16,5, medroxyprogesterone (susp. for injection 150 mg/ml) – $21,8, levonorgestrel releasing intrauterine system (LNG-IUS) – $87, dienogest (tab. 2 mg) – $111, 7. The average cost of herbal medicines along with the recommendation of long-term monitoring was $26,7 in 30% of patients. Other patients were treated symptomatically with antibiotics, antiprotozoal medicines for an average 10 days (jozamycin, clindamicin+clotrymazol, ciprofloxacin+ornidazole, doxycycline). CONCLUSIONS: Accessibility and usability of patients’electronic databases provides a dataset for healthcare system stakeholders to make rational and evidence-based decisions about whether a particular treatment should be approved or reimbursed on the local and national level.