BACKGROUND: It is well documented that geographic and economic factors are key determinants for accessibility to healthcare. The Argentinean Republic went through economic turmoil in 2014, with its GDP decreasing from US$ 613 to US$ 547 billion. Healthcare expenditure (private and public) accounts 8% of GDP, with large urban centers concentrating the majority of healthcare (HC) facilities.  OBJECTIVES: Analyze and evaluate the relevance of geographic and economic factors that allows access to HC facilities in large Argentinean Urban Centers. METHODS: Quantitative analysis of demographic and hHC related resource use variables in the Argentinean Metropolitan (Metro) and other 5 large regional areas was performed by market research; the former were classified by HC-related resource intensity (low, middle and high) according the percentage of GDP spent in  HC (%HCE) and number of hospital beds (Acute and chronic). Population (Pop), per-capita health expenditure (PCHE), out of pocket expenditure (OOP) was obtained per each of them. Results are shown as percentage and net values.  RESULTS: Pop: 43 million, HC expenditure: USD 44 billion, PCHE: USD 1.026, OOP: USD 203 (20% of the PCHE). Metro area represents 33% of total national Pop, exercising 42% of total HC expenditure; PCHE was USD1.247,  OOP/PCHE 27% and 38.590 HBs. High resource areas were Buenos Aires, La Pampa and Córdoba (central region), comprising 56% of total HC expenditure; PCHE was USD2.982, OOP/PCHE 61% and 42.160 HB. Medium resource areas included Patagonia (south) & the northwest, representing 13% of HC expenditure; PCHE was USD2.134, OOP/PCHE 15% and 14.519 BD. Low resource areas included the northeast area, with only 5% of HC expenditure, PCHE USD637, OOP/PCHE 24% and 9.642 HB.  CONCLUSIONS: Despite significant HC resources dedicated to Metro and central areas, large OOP% are being observed. The fragmentation of health system contributes with resource dispersion. Adequate resource distribution is key to guarantee HC access to the population.