A PREVALENCE STUDY ON GESTATIONAL HYPERTENSION AND ASSOCIATED COMPLICATIONS IN PREGNANT WOMEN

Author(s)

Ahmad M1, Masood I1, Usman Minhas M1, Noman ul Haq N2
1The Islamia University of Bahawalpur, Bahawalpur, Pakistan, 2University of Balochistan, Quetta, Pakistan

OBJECTIVES: Hypertensive disorders of pregnancy (HDP) are a group of common medical complications in pregnancy, and also a major cause of maternal and neonatal mortality and morbidity. Hypertension complicates up to 10% of all pregnancies. It is divided mainly into four types; pregnancy-induced hypertension, preeclampsia, eclampsia and gestational hypertension. HDP are associated with a number of maternal and fetal complications. Maternal consequences are placental abruption, venous thromboembolism, renal impairment, respiratory distress, liver failure and death. HELLP* syndrome complicates severe pre-eclampsia and eclampsia. Fetal complications include intrauterine growth restriction (IUGR), fetal distress, neonatal asphyxia, preterm birth and intrauterine fetal demise. The study aim was to explore and identify various factors that are major reasons for deaths and complications arising due to pregnancy induced hypertension.  METHODS: A retrospective study was conducted on the cases of HDPin gynecology ward of Bahawal Victoria Hospital (BVH) in Bahawalpur, Southern Punjab of Pakistan. All the factors were compared with three variables; age, miscarriage and trimester. RESULTS: Miscarriage frequency was more (64.3%) in women with low lymphocyte values. In 1st trimester HELLP was recorded only in 1 case only while all other types of hypertension were not present in any case. In 2nd trimester gestational HTN was 22.2%, Pregnancy-induced hypertension (PIH) was 44.4%, pre-eclampsia was 18.5%, eclampsia was 14.8%. In 3rd trimester gestational HTN was 0%, PIH was 59.9%, pre-eclampsia was 22.8%, eclampsia was 16.9% and HELLP was 0.4%. Still births occurred in 2nd (51.9%) and 3rd (17.7%) trimester. While preterm births in 2nd and 3rd trimester were 48.1% and 28.7% respectively. CONCLUSIONS: HDP is causing a number of maternal and fetal complications, with major contribution to placental abruption and intrauterine growth restriction. Preeclampsia and eclampsia were associated with higher rate of fetal and/or maternal mortality.

Conference/Value in Health Info

2016-05, ISPOR 2016, Washington DC, USA

Value in Health, Vol. 19, No. 3 (May 2016)

Code

PRM10

Topic

Clinical Outcomes

Topic Subcategory

Clinical Outcomes Assessment

Disease

Cardiovascular Disorders

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