TREATMENT PATTERN AND OUTCOMES OF INTRAVENOUS ANTIHYPERTENSIVE AGENTS IN US HOSPITAL ICH PATIENTS

Author(s)

Wang Y, Plent S, Crothers TA
The Medicines Company, Parsippany, NJ, USA

OBJECTIVES: In patients with spontaneous intracerebral hemorrhage (ICH), current guidelines recommend managing elevated blood pressure (BP) with intermittent or continuous infusion of intravenous medications. The purpose of this retrospective observational study is to evaluate the clevidipine (CLV) usage patterns and patient outcomes of continuous infusion intravenous antihypertensive agents (IVAH) compared to other agents available.    METHODS: Study data were extracted from the Premier hospital database. ICH patients were identified by primary diagnosis ICD-9 CM codes of 431 (ICH) or 432 (other or unspecified ICH) and a final MS-DRG of 64, 65, 66 (Intracranial hemorrhage or cerebral infarction). Patients who received clevidipine, nicardipine, or nitroprusside during the first two days of admission between January 2009 and June 2014 were included.  Baseline demographics, outcomes, and costs were evaluated and propensity score matching comparing CLV to nicardipine (NIC) and CLV to nitroprusside (SNP) was performed to control for confounders. RESULTS:

Conference/Value in Health Info

2015-05, ISPOR 2015, Philadelphia, PA, USA

Value in Health, Vol. 18, No. 3 (May 2015)

Code

PCV130

Topic

Health Service Delivery & Process of Care

Topic Subcategory

Treatment Patterns and Guidelines

Disease

Cardiovascular Disorders

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