Patients with COPD experience lower levels of health related quality of life (HRQoL). Social and emotional support has been found to improve mental and physical health and reduce mortality. Few studies have investigated the impact of social and emotional support among patients with COPD. OBJECTIVES: To examine the impact of social and emotional support on HRQoL, disability and depression among COPD patients METHODS: We utilized data from the 2013 Behavioral Risk Factor Surveillance System (BRFSS) to match self-reported COPD patients who receive emotional/social support (63%) with those who rarely/never (37%) receive that support based on a propensity score model. We used the STATA command psmatch2 to perform 1:1 nearest neighbor matching without replacement, and caliper width was set at 0.01. Adequacy of matching was assessed by estimating the standardized differences between the matched pairs for all variables. We compared the HRQoL domains (general, physical, mental health and activity limitation), depression and disability for the matched cohort using the McNemar’s test.  RESULTS: After propensity score matching, standardized differences between groups were <10% for all matched variables (demographics, smoking, exercise, and comorbidities), indicating adequate matching between each level of emotional support.  COPD patients who rarely/never receive emotional/social support were more likely to experience more poor physical HRQoL days (n= 307 pairs, odds ratio (OR)=2.13, 95% confidence interval (CI):1.52-3.03, p<0.001), poor mental HRQoL days (n=300 pairs ,OR=1.59, CI:1.11-2.72, p=0.007), days of activity limitations (n=319 pairs, OR=1.92, CI:1.4-2.7, p<0.001) and depression (n= 321 pairs, OR=1.59, CI:1.1-2.33, p <0.001).   Poor general health and disability were not significantly associated with emotional/social support. CONCLUSIONS: Among COPD patients, inadequate emotional and social support is associated with depression and impairments of most HRQoL domains. Recognition of the importance of emotional and social support by family members, healthcare providers and policy makers is important to improve functioning among COPD patients.