THE BURDEN OF GOUT IN A CANADIAN PRIMARY CARE POPULATION

Author(s)

Williams DM1, Cowan C1, Gendron A1, Goodfield J2, Oraichi D2, Fischer A2, Borrelli R2, Liu N2, Dziarmaga A1
1AstraZeneca Canada Inc., Mississauga, ON, Canada, 2IMS Brogan, Mississauga, ON, Canada

OBJECTIVES: Gout, a common arthritis, causes significant burden on patient’s quality of life and the health-care system. The objectives of this study were to understand a gout population in terms of demographics, clinical characteristics, healthcare utilization and costs versus a gout-free population. METHODS: This retrospective study is one portion of an overall gout study, which used data extracted from IMS Evidence 360 EMR Canada, a primary care electronic medical records database in Ontario. Gout patients were selected if they had ≥1 gout diagnosis and/or ≥1 gout medication claim (index date) from 1 July 2008 to 30 June 2012. Gout patients were matched 1:5 to gout-free patients based on demographics and comorbidities using an adapted version of the Charlson Comorbidity Index (CCI). All patients were followed for two years post-index date. Costs were limited to primary care physician visits. RESULTS: There were 676 gout patients; 77% were male with mean age of 58 years, which matched closely to gout-free patients. Mean CCI score at baseline was 1.08 in both groups. Over the two-year follow-up, gout patients were significantly more likely to have cardiovascular disease (61% vs. 40%), dyslipidemia (43% vs. 29%), obesity (26% vs. 14%), and diabetes (22% vs. 17%, all p<0.01) vs the gout-free cohort. Gout patients’ lab results (BMI, BP, eGFR, lipids) deviated from normal more than gout-free controls. Gout patients incurred a significantly higher number of annual physician visits (5 vs. 2.5), lab tests (24 vs. 4.5), and had a greater percentage with specialist referrals (58% vs. 46%, all p<0.0001) leading to higher healthcare costs. CONCLUSIONS: Gout is associated with high disease burden in a Canadian primary care setting, which is consistent with previous publications. Gout patients were more likely to have significant comorbidities, farther-from-normal lab results, and higher healthcare utilization and costs compared to gout-free patients.

Conference/Value in Health Info

2015-05, ISPOR 2015, Philadelphia, PA, USA

Value in Health, Vol. 18, No. 3 (May 2015)

Code

PHS159

Topic

Health Service Delivery & Process of Care

Topic Subcategory

Health Care Research

Disease

Musculoskeletal Disorders

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