OBJECTIVES: Use of potentially inappropriate medications (PIMs) among the elderly is a serious public health problem because it is intrinsically linked to increased morbidity and mortality, causing the high costs to public health systems. Objectives of this study were to determine the prevalence and predictors of PIM prescribing in elderly inpatients using STOP and START criteria METHODS: The prospective observational study was carried at a private tertiary care hospital. Prescriptions of elderly inpatients aged 60 years and above were collected and analyzed. PIMs were identified with the help of STOP and START criteria. Predictors associated with use of PIMs were identified by bivariate and multivariate logistic regression analysis. RESULTS: The results were based on data of 60 patients. More than half (56%) were males and 50% were aged between 60–69 years with a mean average age of 69 years. Mean number of diagnoses and medications were two and nine, respectively. A total of 18 (30%) patients were prescribed with  at least 1 PIM according STOP Criteria. Most commonly prescribed PIMs were systemic corticosteroids (29%) followed by theophyline (18%) and betablockers (10%). On multivariate regression, important predictors for PIM prescribing were found to polypharmacy, number of diagnoses. CONCLUSIONS: The results show that PIMs prescribing is high in Indian elderly inpatients STOP and START criteria, it is more effective in identifying the PIMs. This study is ongoing and we will present the  data upto 250 patents before the presentation.