OBJECTIVES: This study aimed to assess the level of medication adherence among patients with non-communicable chronic diseases in Quetta Baluchistan, Pakistan METHODS: A cross sectional study was conducted among patients with non- chronic diseases,  visiting outpatient department in public/private hospitals and clinics of Quetta city. Morisky Medication Adherence Scale (Urdu version) was used to collect the data. The descriptive statistics was used to present the demographic and disease related information. Inferential statistics was used to  the evaluation relationship among study variables. All analyses were performed using SPSS 20.0. RESULTS: A total of 505 patients with non- chronic diseases (Diabetes, Hypertension, Heart diseases, Asthma and others) were enrolled for the present study. The mean age of the patients was 44.9 years, majority 304 (60.2%) were females. The proportions of diseases were; diabetes (45.1%) hypertension (26.5%) heart diseases (7.3%) asthma (6.3%) mainly and other (14.7%). A very small proportion of the patient 11.1% were having good medication adherence while 27.9% were having moderate adherence and 61.0% exhibited poor adherence. CONCLUSIONS: The study concluded that level of medication adherence among patients with non- communicable chronic disease was very poor, efforts should be made to identify the factors associated with non-adherence so that level of adherence should be improved to achieve better therapeutic outcome.