OBJECTIVES: Most endocrine disorders are chronic diseases that need life-long care. Some of the most common endocrine diseases include diabetes mellitus, hypothyroidism and metabolic syndrome. Although most of the patients suffering of these diseases are followed by their primary care physician, definite diagnosis, initiation/change of treatment and chronic care of the disease is ensured by the endocrinologist. The objective of this study was to evaluate an endocrinologist electronic medical record (EMR) database to assess its feasibility for use in observational studies. METHODS: We analyzed de-identified patient data from Longitudinal Patient Database (LPD) Endocrinologist panel, including endocrinologists from 2013-2014. Comprehensiveness and completeness of each variable by visit was evaluated. Characteristics of physicians and patient population were compared to published sources. RESULTS: There were 77 243 visits by 34 492 active patients (= 1 visit per year) to 40 physicians. Completeness of each variable by visit ranked from 100% to 27% for sex, age and laboratory results. Most of these patients (73%) were female. Analysis of diagnosis associated to visits revealed that 32 % were related to diabetes, while 32% and 9% were related to thyroid disorders and obesity respectively. Among diabetic patients, 50% were female, and 74% had type 2 diabetes. An average BMI of 30 and HbA1C of 7.4% was recorded. Among treated patients 38% received sulfonylureas and 59 % biguanides. A third of the patients (34%) received one, another third (33%) received two, and another third (33%) three or more anti-diabetic treatments (including insulin). Insulin was prescribed, alone or in combination, in 36% of cases. The comparison of these data with literature is presented. CONCLUSIONS: This panel is still new and needs further validation studies. Good agreement with published data suggests this may be a valuable tool to support observational studies.