AN ANALYSIS OF NICE RECOMMENDED IN LINE WITH CLINICAL PRACTICE HEALTH TECHNOLOGY ASSESSMENT DECISIONS

Author(s)

O'Neill P1, Chapman AM1, Devlin N1, Duran A2
1Office of Health Economics, London, UK, 2Pfizer Ltd, Surrey, UK

OBJECTIVES: Between January 2007 and September 2014 NICE report that they have made 65 health technology assessment decisions categorised by them as a “recommended in line with clinical practice” (RiLwCP).  This categorisation is not explained and implications for patient access are not clear.    Using a previously developed method, we calculate the degree of recommended access for these decisions.  In order to facilitate understanding we also develop a taxonomy for the factors underlying these decisions.  METHODS: In a previously published paper we developed a measure, M, to summarise access associated with NICE technology optimised appraisal decisions. This was defined as M=(p/P)X100, where M is a measure of the level of patient access (0 equals no access, 100 full access), P is the set of patients considered in the guidance as potential candidates for treatment (given the scope of appraisal and license), and p is the number of patients for whom NICE did recommend.   We applied measure M to the 65 RiLwCP decisions made between January 2007 and September 2014.  Then assessing the guidance documents published for these decisions we identified six themes driving specific recommendations: reference to a previous NICE TA, existence of a relevant clinical guideline, the technology fits within an established pathway of care, clinical opinion, clinical/cost-effectiveness matching, non-pharmaceutical.  RESULTS: For 65 decisions between January 2007 and September 2014 M was 66.    Among the factors underlying RiLwCP decisions the most common were instances where the committee matched cost and clnical effectiveness evidence, doing so in 37% of cases.    CONCLUSIONS: The results for this period suggest that many RiLwCP decisions have the same characteristics as those classified as “optimised” by NICE; notably that use is restricted to a subgroup of patients relative to license and this is done for clinical and/or cost effectiveness considerations.

Conference/Value in Health Info

2015-05, ISPOR 2015, Philadelphia, PA, USA

Value in Health, Vol. 18, No. 3 (May 2015)

Code

PHP148

Topic

Health Technology Assessment

Topic Subcategory

Decision & Deliberative Processes

Disease

Multiple Diseases

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