UTILITY ELICITATION FOR ALLERGIC RHINOCONJUNCTIVITIS AND ASTHMA IN CHILDREN

Author(s)

Grand TS¹, Retzler J², Smith AB², Romano RM¹, Domdey A¹
¹ALK, Hørsholm, Denmark, ²York Health Economics Consortium Ltd, York, UK

Presentation Documents

PRS49--strong-u-grand-ts-u-sup-1-sup-strong-retzler-j-sup-2-sup-smith-ab-sup-2-sup-romano-rm-sup-1-sup-domdey-a-sup-1-sup-br-sup-1-sup-alk-horsholm-denmark-sup-2-sup-york-health-economics-consortium-ltd-york-uk

OBJECTIVES: This study aimed to generate utility and disutility values for seasonal allergic rhinoconjunctivitis (ARC) and asthma in children, in order to demonstrate the impact of these conditions on patients' health-related quality of life.

METHODS: Health state descriptions were developed using clinical guidelines, Allergic Rhinitis and its Impact on Asthma (ARIA) and Global Initiative for Asthma (GINA) to incorporate symptoms, impact on daily life, as well as treatments required. Descriptions were amended with clinician and patient input, and adapted for lower reading ages. An online survey presented respondents with the health state descriptions in a randomised order. After each description, respondents rated the health state using a visual analogue scale (VAS). The survey was distributed to children aged 8 to 11 from four European countries (UK, France, Germany, Slovakia) via consenting parents recruited by a third party panel company. Average utility and disutility values were calculated.

RESULTS:

CONCLUSIONS: More severe health states resulted in lower utility values. Disutility values were highest for changes between the mildest and most severe health states. ARC with and without WPCA has considerable negative impact on quality of life in children.

Conference/Value in Health Info

2017-11, ISPOR Europe 2017, Glasgow, Scotland

Value in Health, Vol. 20, No. 9 (October 2017)

Code

PRS49

Topic

Patient-Centered Research

Topic Subcategory

Health State Utilities

Disease

Respiratory-Related Disorders

Presentation