PREVALENCE OF ANTICONVULSANTS UTILIZATION AT A TERTIARY HOSPITAL IN SOUTHEAST NIGERIA; BRIDGING THE GAPS BETWEEN FACILITIES OUTCOMES AND POLICIES THROUGH EVIDENCE-BASED REPORTS
Author(s)
Ogbonna BO
Nnamdi Azikiwe University Awka, Awka, Nigeria
OBJECTIVES: The World Health Organization (WHO) recommended regular drug utilization studies in health facilities as a tool in generating information on disease pattern, and as a guide for policy in healthcare systems. These information help in assessing disease patterns, population health status, quality of care, quality of prescribers, and treatment practices. The choice of anticonvulsants depends on individual tolerance, affordability, and efficacy. This study assessed the proportions of anticonvulsants used and determined the most commonly used anticonvulsants. METHODS: The study was a retrospective cross sectional analysis of prescription records. Study lasted between June to December 2016. Data were analyzed based on frequency of prescribed drugs, number of drugs, defined daily dose (DDD), number and frequency of anticonvulsants used. RESULTS: The number of prescriptions analyzed was 1393.0. Of these prescriptions, 7700.0 drugs were prescribed with each prescription containing an average of 5.5±0.9 drugs per prescription. The mean age of patients was 46±4.3 years. Anticonvulsant drugs accounted for 19.0 (0.25%) of the entire drugs prescribed. Carbamazepine was the most prescribed anticonvulsant 12.0 (63.2%) at a dose of 200mg daily, followed by diazepam 6.0 (31.6%), while the least was pregabalin 1.0 (5.2%). Generic prescription of carbamazepine was 84.0% while that of diazepam was 100.0%. Prescription of anticonvulsants monotherapy was 100.0%. CONCLUSIONS: Study suggested low anticonvulsants use an indication of low prevalence of seizure related disorders in the population. Patients were controlled on monotherapy. Carbamazepine was the most used anticonvulsant and suggested good tolerance, efficacy, affordability, and acceptability. The study provided baseline information for further studies to provide timely information for promoting anticonvulsant drugs utilization in healthcare facilities in Nigeria. Policy issues on the use of newer agents should be dependent on facility-based studies. Newer agents can be introduced when they match and exceed already existing ones based on key indicators.
Conference/Value in Health Info
2017-11, ISPOR Europe 2017, Glasgow, Scotland
Value in Health, Vol. 20, No. 9 (October 2017)
Code
PND69
Topic
Health Service Delivery & Process of Care
Topic Subcategory
Health Care Research
Disease
Neurological Disorders