MONTECARLO MODEL AS A TOOL IN ESTIMATION OF ECONOMIC BURDEN OF A DISEASE THROUGH THE PREDICTION OF BIOLOGICAL CHARACTERISTICS OF TUMOR IN BREAST CANCER

Author(s)

Balderas-Peña L1, Sat-Muñoz D2, Martinez-Herrera B3, Avalos-Nuño J4, Gonzalez-Barba F1, Cruz-Corona E1, Ortiz-González F5
1UMAE Hospital de Especialidades Centro Médico Nacional de Occidente IMSS, Guadalajara, Jalisco, Mexico, 2Universidad de Guadalajara. Centro Universitario de Ciencias de la Salud, Guadalajara, Jalisco, Mexico, 3Hospital General de Zona No. 2 "Dr. Francisco Padrón Puyou", San Luis Potosí, SLP, Mexico, 4UMAE Hospital de Gineco-Obstetricia Centro Médico Nacional de Occidente IMSS, Guadalajara, Jalisco, Mexico, 5Unidad Médica de Alta Especialidad Hospital de Especialidades. Centro Médico Nacional de Occidente, Guadalajara, Jalisco, Mexico

INTRODUCTION

The third-party payer whom provide health services around the world need mathematical and methodological tools to estimate the future expenditures related health services in different populations. We use breast cancer data to generate a predictive mathematical model as help to estimate the health services’ cost in the context of a developing country as Mexico.

OBJECTIVES

:
To evaluate the concordance between observed and calculates expenditures in the treatment of a sample of breast cancer patients attended in a Mexican public health institution.

METHODS

:
Were reviewed the clinical records from 407 breast cancer women to calculate through micro-costing, the total expenditure in health during their treatment. After that was generated the Montecarlo mathematical predictive model to try to estimate the health services expenditure in a 100 women hypothetical sample, simulating the clinical characteristics, as primary tumor size, clinical stage, histologic features, lymphatic ganglia, surgery, radiotherapy and chemotherapy kind, metastases, metastasis anatomic localization, and recurrence treatment. Chi squared and student T test for independent samples were used to estimate p value between studied patients and hypothetical population.

RESULTS

:
Were not found statistical differences between clinical stage ((p=0.865), tumor receptors (p=0.893), and kind of metastases between patients sample and hypothetical sample (p=0.699). The mean cost for the breast cancer women sample was $251,454.43 MXN, and for hypothetical sample $329,503.85 MXN (p<0.05), however we did not find differences in surgical procedures cost (p=0.441)

CONCLUSIONS

:
The Montecarlo predictive model could be a useful tool to estimate the health services expenditure and to calculate a budget close to real cost

Conference/Value in Health Info

2017-11, ISPOR Europe 2017, Glasgow, Scotland

Value in Health, Vol. 20, No. 9 (October 2017)

Code

PRM54

Topic

Economic Evaluation, Methodological & Statistical Research

Topic Subcategory

Confounding, Selection Bias Correction, Causal Inference, Cost/Cost of Illness/Resource Use Studies, Modeling and simulation

Disease

Oncology, Reproductive and Sexual Health

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