INCIDENCE AND PREVALENCE OF PAINFUL DIABETIC NEUROPATHY AND POSTHERPETIC NEURALGIA IN MAJOR 5 EUROPEAN COUNTRIES, THE UNITED STATES AND JAPAN
Author(s)
Risson V1, Nallagangula TK2, Vasanthaprasad V2
1Novartis Pharma AG, Basel, Switzerland, 2Novartis Healthcare Pvt. Ltd., Hyderabad, India
Presentation Documents
OBJECTIVES: The objective of this review was to collate evidence on the incidence and prevalence of painful diabetic neuropathy (PDN) and postherpetic neuralgia (PHN) in 5 major European countries (United Kingdom [UK], Germany, France, Italy and Spain), the United States (US) and Japan. METHODS: A narrative review was conducted through searching Embase®, MEDLINE® and Cochrane databases, from 2010 to February 2017. The incidence and prevalence data obtained was summarised according to geographies. RESULTS: Of 4,425 citations reviewed, 26 studies reported the incidence and/or prevalence of PDN and/or PHN. The included studies were diverse in their study designs: population based studies, surveys, cross-sectional/longitudinal, prospective/retrospective and single/multicentre. The incidence of PDN was and prevalence varied from 8.2% to 25.7% (US), among all diabetic patientsprediabetes (4.2% [Germany] to 16.0% [US]). Studies differed in their respective diagnosis of PDN; different PRO instruments or PRO instrument combined with clinical examination. The incidence of PHN varied from 1.2% (Germany) to 47.6% (Spain) and the prevalence varied from 6.0% (Italy) to 59.2% (Spain) CONCLUSIONS: Although a reasonable body of research was identified for both PDN and PHN, heterogeneity in study designs and diagnostic criteria limits the ability to generalise and compare incidence and prevalence across geographies. Studies from diverse populations and of larger sample size are needed to expand our insight on the incidence and prevalence of PDN and PHN.
Conference/Value in Health Info
2017-11, ISPOR Europe 2017, Glasgow, Scotland
Value in Health, Vol. 20, No. 9 (October 2017)
Code
PSY19
Topic
Epidemiology & Public Health
Disease
Systemic Disorders/Conditions