HEPATITIS A AND HEPATITIS B RECOMBINANT VACCINE ADHERENCE IN THE UNITED STATES
Author(s)
Trantham L1, Kurosky S1, Zhang D2, Lu IX3, Johnson KD2
1RTI Health Solutions, Research Triangle Park, NC, USA, 2Merck & Co., Inc., Kenilworth, NJ, USA, 3MSD, Lyon, France
OBJECTIVES: Estimate the completion and adherence of the HepA/HepB recombinant vaccine three-dose schedule in the US. METHODS: We conducted a retrospective database study of claims from the 2008-2015 MarketScan Commercial Claims and Encounters (CCAE), Medicare Supplemental, and Medicaid databases. Completion of 2 and 3 doses of Twinrix and adherence with the 3-dose recommended schedules were measured. Individuals age ≥ RESULTS: CONCLUSIONS: Adherence to the recombinant HepA/HepB vaccine regimen is suboptimal. Only 18% received the third dose within the recommended schedule. Research is needed to fully understand the factors associated with completion and adherence to multi-dose vaccines in order to improve vaccination rates.
Conference/Value in Health Info
2017-11, ISPOR Europe 2017, Glasgow, Scotland
Value in Health, Vol. 20, No. 9 (October 2017)
Code
PIN72
Topic
Patient-Centered Research
Topic Subcategory
Adherence, Persistence, & Compliance
Disease
Infectious Disease (non-vaccine)