FACTORS ASSOCIATED WITH MEDICATION ADHERENCE IN KOREAN POSTMENOPAUSAL OSTEOPOROSIS(PMO)- RESULTS FROM PMO OUTCOMES RESEARCH(OR)
Author(s)
Min Y1, Byun D2, Moon S3, Kim T4, Kim HJ5, Kim Y5
1Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South), 2Soonchunhyang University Hospital, Seoul, Korea, Republic of (South), 3Yonsei University College of Medicine, Seoul, Korea, Republic of (South), 4College of Medicine, Korea University, Seoul, Korea, Republic of (South), 5Pfizer Pharmaceuticals Korea Ltd., Seoul, Korea, Republic of (South)
OBJECTIVES: This analysis was proposed to investigate factors associated with medication adherence in PMO patients of Korea. METHODS: Data in this analysis were from PMO OR, a cross-sectional study from March 2013~July 2014 with 29 participating general-hospitals. Patients’ demographic, clinical characteristics, and treatment patterns were collected from medical chart review, and patient-reported outcomes on treatment satisfaction and medication adherence were measured by 14-item Treatment Satisfaction Questionnaire for Medication(TSQM) and Osteoporosis-Specific Morisky Medication Adherence Scale(OS-MMAS), respectively. Multiple logistic regression analysis was conducted to investigate factors associated with adherence(Low-adherence; OS-MMAS score<8, high-adherence; score=8). RESULTS: Of total 1,804 patients(mean age 62.33±, 95%CI:1.022-1.046). Per treatment pattern, use of HT(OR=0.732, 95%CI:0.198-0.730) compared to BPP was negatively associated with adherence. There was no significant difference in adherence between SERM and BPP. CONCLUSIONS: Among the identified factors associated with medication adherence from this study, choice of treatment agent, frequency of drug usage, and considerations for patients’ GI symptoms are adjustable during the course of treatment. Such strategic adjustments are critical for providing effective PMO treatment.
Conference/Value in Health Info
2017-11, ISPOR Europe 2017, Glasgow, Scotland
Value in Health, Vol. 20, No. 9 (October 2017)
Code
PIH19
Topic
Patient-Centered Research
Topic Subcategory
Adherence, Persistence, & Compliance
Disease
Musculoskeletal Disorders, Reproductive and Sexual Health