OBJECTIVES: To evaluate the clinical effectiveness of Varee Vidaryadi Kashayam and Brihathyadi Kashayam in Lower Urinary Tract Infection

METHODS: : A randomized single blind clinical study with pretest and posttest design in 3 groups’ standard and trails were adopted, where the patients were given treatment with specific duration with follow up. In total 480 diagnosed Lower urinary tract infection patients were selected irrespective of their sex and age group of 16-70 from the OPD and IPD of Muniyal Institute of Ayurveda Medical Sciences, Manipal, enrolled for the present study out of which 27 were dropped out. Routine hematological, Bio-chemical, urine analysis were recorded. The main signs and symptoms frequent micturition, yellowish urine, redish blood mixed, Painful micturition, Burning micturition, were taken for the assessment as symptoms grade parameters. Urine RBC and Pus cells, ESR also taken for the assessment as Laboratory parameters. Data obtained from the above mentioned study was statistically analyzed by using the Z and f tests.

RESULTS: In group A-Varee Vidaryadi Kashayam 10% were assessed under Complete cured 15% under Marked improved and 45% under Moderate improved category. in group B-Brihathyadi Kashayam 5% were assessed under complete cured 20% under Marked improved and 20% under Moderate improved category. In group C Norfloxacine 15% were assessed under Complete cured 60% under Marked improved and 25% under Moderate improved category. The study reveals Urine RBC 60.53%, 75.68%, 74.19% Urine pus cells 51.22%, 48.89%, 72.97% ESR 36%, 35%, 70% in 3 groups respectively which were statistically highly significant result p<0.001.

CONCLUSIONS: Study concluded both the groups are effective treatment in Lower urinary tract infection and Group A Varee Vidaryadi Kashayam was more effective than group B Brihathyadi Kashayam